Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination | NEJM


Original Article from The New England Journal of Medicine — Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination

Fonte: Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination | NEJM

Síndrome pós-aguda por Covid-19


https://www.nature.com/articles/s41591-021-01283-z.pdf?fbclid=IwAR3RjmPqJ_E4nN23TBb5phDlASXwHE4EbpwuMEKob3mACxcGHgyt5Yy-otU

Artigo da nature.
Síndrome pós-aguda COVID-19
Uma revisão abrangente da literatura atual sobre COVID-19 pós-aguda, a sua patofisiologia e as suas sequelas específicas para os órgãos.

Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives

Fonte: Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives

Nature: SARS-CoV-2 receptor is co-expressed with elements of the kinin–kallikrein, renin–angiotensin and coagulation systems in alveolar cells

SARS-CoV-2, the pathogenic agent of COVID-19, employs angiotensin converting enzyme-2 (ACE2) as its cell entry receptor. Clinical data reveal that in severe COVID-19, SARS-CoV-2 infects the lung, leading to a frequently lethal triad of respiratory insufficiency, acute cardiovascular failure, and coagulopathy.

Elevated D-dimers and lack of anticoagulation predict PE in severe COVID-19 patients | European Respiratory Society

Elevated D-dimers and lack of anticoagulation predict PE in severe COVID-19 patients | European Respiratory Society
— Ler em erj.ersjournals.com/content/56/4/2001811

Association Between Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19


This meta-analysis pools data from 7 randomized trials to estimate the association between administration of corticosteroids vs usual care or placebo and all-cause mortality at 28 days in patients with severe coronavirus disease 2019 (COVID-19).

Fonte: Association Between Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

Covid-19: Do many people have pre-existing immunity?

www.bmj.com/content/bmj/370/bmj.m3563.full.pdf

It seemed a truth universally acknowledged that the human population had no pre-existing immunity to SARS-CoV-2, but is that actually the case? Peter Doshi explores the emerging research on immunological responses.

Case Report: Recurrent Clinical Symptoms of COVID-19 in Healthcare Professionals: A Series of Cases from Brazil

We describe six cases of healthcare professionals in Brazil who recovered but again presented symptoms consistent with COVID-19, with new positive reverse transcription (RT)-PCR test results.

COVID-19 is, in the end, an endothelial disease | European Heart Journal | Oxford Academic

Abstract. The vascular endothelium provides the crucial interface between the blood compartment and tissues, and displays a series of remarkable properties tha
— Ler em academic.oup.com/eurheartj/article/41/32/3038/5901158

Thrombosis and COVID-19 pneumonia: the clot thickens!


https://erj.ersjournals.com/content/56/1/2001608

A trombose pulmonar parece ser comum na pneumonia COVID-19 e assume duas formas, embolia pulmonar proximal e / ou trombose distal. Os possíveis mecanismos e implicações clínicas são discutidos.