Association Between Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19


This meta-analysis pools data from 7 randomized trials to estimate the association between administration of corticosteroids vs usual care or placebo and all-cause mortality at 28 days in patients with severe coronavirus disease 2019 (COVID-19).

Fonte: Association Between Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19

Corticoides‌ ‌diminuem‌ ‌mortalidade‌ ‌em‌ ‌casos‌ ‌graves‌ ‌de‌ ‌Covid-19,‌ ‌confirmam‌ ‌estudos‌


Dois estudos publicados nesta quarta-feira, 2 de setembro, confirmam a utilidade desses fármacos na terapia de casos graves da Covid-19, também marcados por uma reação inflamatória exagerada.

Fonte: Corticoides‌ ‌diminuem‌ ‌mortalidade‌ ‌em‌ ‌casos‌ ‌graves‌ ‌de‌ ‌Covid-19,‌ ‌confirmam‌ ‌estudos‌

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report | NEJM


Original Article from The New England Journal of Medicine — Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

Fonte: Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report | NEJM

Saindo do forno o trabalho sobre o benefício do corticoide em pacientes com COVID. Ansiosamente aguardado!!

Finally: Common Drug Improves COVID-19 Survival in Trial


‘A ground-breaking development,’ according to preliminary data from an ongoing trial

Fonte: Finally: Common Drug Improves COVID-19 Survival in Trial

”dexametazona em pacientes necessitando de suplementação de O2 ou ventilação mecânica.

Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS | NEJM

Original Article from The New England Journal of Medicine — Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS

Fonte: Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS | NEJM

 Um conceito interessante, que abre uma linha de conduta promissora.

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock | NEJM

Original Article from The New England Journal of Medicine — Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

Fonte: Hydrocortisone plus Fludrocortisone for Adults with Septic Shock | NEJM

E esse é o outro.

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock | NEJM

Original Article from The New England Journal of Medicine — Adjunctive Glucocorticoid Therapy in Patients with Septic Shock

Fonte: Adjunctive Glucocorticoid Therapy in Patients with Septic Shock | NEJM

A última edição online da NEJM veio com dois artigos interessantes sobre o uso de corticosteróides em sépsis, com resultados não exatamente concordantes. Esse é um deles.

Corticosteroids in treating community-acquired pneumonia: has the time really come? – Clinical Microbiology and Infection

Fonte: Corticosteroids in treating community-acquired pneumonia: has the time really come? – Clinical Microbiology and Infection

Oh God! Here we go again!