Fonte: The Lancet Zika virus resource centre
Página do “The Lancet” com vários links, todos ligados ao tema Zika. Ideal para quem quer fazer algum trabalho ou simplesmente dar uma aprofundada no assunto.
Artigo médico
New Vaccines against Epidemic Infectious Diseases — NEJM
Perspective from The New England Journal of Medicine — New Vaccines against Epidemic Infectious Diseases
Fonte: New Vaccines against Epidemic Infectious Diseases — NEJM
Dengue virus (DENV)-specific antibodies enhance Brazilian Zika virus (ZIKV) infection | Read by QxMD
Anti-Flavivirus antibodies are highly cross-reactive and may facilitate Zika virus (ZIKV) infection through the antibody-dependent enhancement (ADE) mechanism. We demonstrate that dengue-specific antibodies enhance the infection of a primary Brazilian ZIKV isolate in FcγRII-expressing K562 cell line. In addition, we demonstrate that serum samples from dengue-immune pregnant women enhanced ZIKV infection. These findings highlight the need of epidemiological studies and animal models to further confirm the role of ADE in the development of congenital and neurological complications associated with Zika virus infections.
Fonte: Dengue virus (DENV)-specific antibodies enhance Brazilian Zika virus (ZIKV) infection | Read by QxMD
Interessante. A presença de anticorpos anti-flavivirus adquiridas devido a uma infecção pela dengue pode potencializar a gravidade de uma infecção subsequente por zika!
Is This Patient Really Allergic to Penicillin?
Here are the questions to ask to evaluate a patient for a true penicillin allergy.
Revisão: Tratamento de MRSA
Diagnosis of opportunistic infections: HIV co-infections – tuberculosis.
diagnosis_of_opportunistic_infections___hiv-99413
Excelente revisão. Muito além do bK de escarro e PPD.
Aos Residentes: leitura obrigatória.
Rapid Sepsis Assessment Highly Accurate Outside ICU
qSOFA good predictor of poor outcomes in ED setting
Could Viral Infection Predispose to Type 1 Diabetes?
Kids with islet autoantibodies were more likely to have had previous enterovirus infection
Why Do Some People Get HIV After Exposure But Others Don’t?
Some HIV-1 strains are able to get past the body’s natural barriers better.
Fonte: Why Do Some People Get HIV After Exposure But Others Don’t?
Você já se perguntou isso? Até então a principal resposta estava em que certas pessoas tem o receptor CCR5 mutante, incapaz de fixar o HIV nos linfócitos. Agora descobre-se outro mecanismo, relacionado ao próprio virus, com implicações no desenvolvimento de vacinas.
Latent Tuberculosis: New Testing Recommendations
CDC supports the new USPSTF recommendations for latent tuberculosis testing, and a larger role for primary care clinicians in identifying patients for testing.
Fonte: Latent Tuberculosis: New Testing Recommendations
Excelente revisão sobre novos e antigos métodos de diagnóstico de tuberculose latente, e o que fazer com essa informação, do ponto de vista do CDC.
blog infectologia em geral 